JULIAN: Every day, all day I work with computers. I usually get hundreds of computers. If
there’s a problem with the computer, we try to fix the computer. I would hope to go back to school and finish my
degree in information technology. I wasn’t able to finish college because it turns out I needed to be fixed
myself. I started to have problems when I couldn’t concentrate. Like, I would have like rapid thoughts. I would
like be like anxious or stressed, and I would be angry, like I got real angry.
JOSE: Julian’s mother and I split up when he was around five, and he lived with his mom for most
of his life—till his early twenties. He came to live with my sister and
I, and he enrolled in college
here. I started noticing a difference in his behavior—around a few months
after he got into college. There
was something different in his eyes.
JULIAN: I really didn’t have an idea what was going on with me. The paranoia got worse and
worse. And then after a while, I started seeing things and hearing things. I was feeling like rage. I told my
aunt that I was feeling aggravated, and after that she said I should go to the hospital. I went to the hospital
and they evaluated me. They gave me some medication. They released me, but my symptoms just kept getting worse
and worse. Sometimes I would wake up and like see things, like geometric shapes and stuff— like in the
floor or like in the wall. And I also had like an episode when I was— there was a fire extinguisher, and
then I started seeing like the bull and the eagle, and I got angry. So, I started to write the bad thoughts that
I was having in my journal.
JOSE: He ended up giving my sister a journal for her to read to see what she thought of it, and
it was very concerning for her. There was one incident—it was violent. He ended up breaking my nephew’s
guitar on the concrete—just smashing it. We didn’t know what to do.
JULIAN: The next day we went to the hospital. After evaluating me throughout the week and
discussing all my symptoms, the doctor said that I have schizophrenia. I was in denial for a while.
JOSE: The accepting part was very difficult for him. He was fighting it for a long time, and he
did not want to take medicine. Until one day, we’re driving in the car, and I think he was planning on moving.
And I told him, “Julian, you can run all you want, but you can’t run away from your mind.”
JULIAN: I couldn’t deny it anymore. I knew I needed help. So, I started reading about
schizophrenia online. I tried a couple different treatments, and then my doctor introduced me to ARISTADA. She
said that ARISTADA is an injection I had the option to get at her office every 2 months. She said it may help me
with my symptoms. After talking about the benefits and the risks, I decided to try it out.
NARRATOR: ARISTADA INITIO® (aripiprazole lauroxil) and
ARISTADA® (aripiprazole lauroxil) may not be right for everyone.
ARISTADA INITIO is a prescription medicine given as a one-time
injection and is used in combination with oral aripiprazole to start ARISTADA treatment, or re-start ARISTADA treatment after a missed dose, when ARISTADA is used for the
treatment of schizophrenia in adults.
ARISTADA is a prescription medicine given by injection by a healthcare professional and used to treat
schizophrenia in adults.
It is not known if ARISTADA INITIO and/or ARISTADA are safe and effective in
children under 18 years of age.
Elderly people with dementia-related psychosis are at increased risk of
death when treated with antipsychotic medicines including ARISTADA INITIO
and ARISTADA. ARISTADA INITIO and ARISTADA are not for the treatment of
people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).
Before you start treatment with ARISTADA INITIO and ARISTADA, tell your
healthcare provider if you have ever taken Abilify®, Abilify Maintena®, or any aripiprazole product before. People who are allergic to
aripiprazole or any of the ingredients in ARISTADA should not receive ARISTADA. People must first tolerate oral
aripiprazole before receiving ARISTADA INITIO or ARISTADA.
The most common side effects of ARISTADA INITIO and ARISTADA include
restlessness or feeling like you need to move (akathisia). These are not all the possible side effects of ARISTADA INITIO and ARISTADA. You should tell your healthcare provider about any
side-effects you have.
When starting ARISTADA, you may receive a one-time injection called ARISTADA INITIO along with 30 mg of oral
aripiprazole. In some cases, your doctor will have you start with 21 days of oral aripiprazole if ARISTADA INITIO is not right for you.
Please watch the additional Important Safety Information contained in this video.
JULIAN: I am doing well on ARISTADA. My schizophrenia symptoms have improved. And I feel lucky
to have support from my dad and my aunt. I really like that ARISTADA is an injection. I don’t have to remember
to take pills every day. I know that this is an ongoing process, so I’m continuing to work with my healthcare
team and my doctor. I’m continuing to work with computers, and I enjoy my job. I try to hang out with my
coworkers and not isolate myself. We just go to the movies and just hang out at their houses and stuff. I go to
support group every third Monday. It’s helpful to hear the stories. It’s like kind of knowing that you’re not
alone out there.
JOSE: He’s working with his doctor and he is staying on top of his treatments. I’m extremely
proud of Julian. It’s just to see him smile and enjoy himself and be around people and see the Julian that I
see, it’s really great. I’m happy for him. My advice to anybody going through this is just be there when they
need you. Just have to be very patient with the person you’re trying to help.
JULIAN: For me, accepting my diagnosis was very important because I could move forward. It was
kind of hard for me to open up to people at first about my condition. But when I did, I felt better. I wanna
move forward and continue my education in cyber security, and I hope to advance my career. I feel hopeful about
my future.
NARRATOR: IMPORTANT SAFETY INFORMATION
Elderly people with dementia-related psychosis are at
increased risk of death when treated with antipsychotic medicines including ARISTADA INITIO and ARISTADA. ARISTADA
INITIO and ARISTADA are not for the treatment of people who have lost touch with reality
(psychosis) due to confusion and memory loss (dementia).
Contraindication: Do not receive ARISTADA INITIO or
ARISTADA if you are allergic to aripiprazole or any of the ingredients in ARISTADA. Allergic
reactions to aripiprazole have ranged from rash, hives and itching to anaphylaxis, which may include difficulty
breathing, tightness in the chest, and swelling of the mouth, face, lips, or tongue.
ARISTADA INITIO and/or ARISTADA may cause serious side effects including:
- Cerebrovascular problems (including stroke) in elderly people with dementia-related psychosis that can lead to death.
-
Neuroleptic malignant syndrome (NMS), a serious condition that can lead to death. Call your
healthcare provider or go to the nearest hospital emergency room right away if you have some or all of the
following signs and symptoms of NMS:
- high fever
- stiff muscles
- confusion
- sweating
- changes in pulse, heart rate, and blood pressure
- Uncontrolled body movements (tardive dyskinesia). ARISTADA
INITIO and ARISTADA may cause movements that you cannot control in your face, tongue, or other
body parts. Tardive dyskinesia may not go away, even if you stop receiving ARISTADA. Tardive dyskinesia may
also start after you stop receiving ARISTADA.
-
Problems with your metabolism such as:
- High blood sugar (hyperglycemia). Increases in blood sugar can happen in some
people who receive ARISTADA INITIO and/or ARISTADA. Extremely high
blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes (such as
being overweight or a family history of diabetes), your healthcare provider should check your blood
sugar before you receive ARISTADA INITIO and/or ARISTADA and during
your treatment with ARISTADA.
-
-
-
Call your healthcare provider if you have any of these symptoms of high blood
sugar:
- feel very thirsty
- need to urinate more than usual
- feel very hungry
- feel weak or tired
- feel sick to your stomach
- feel confused, or your breath smells fruity
-
- Increased fat levels (cholesterol and triglycerides) in your blood
- Weight gain. You and your healthcare provider should check your weight regularly.
- Unusual and uncontrollable (compulsive) urges. Some people taking aripiprazole have had
strong unusual urges such as gambling that cannot be controlled (compulsive gambling). Other compulsive
urges include sexual urges, shopping, and eating or binge eating. If you or your family members notice that
you are having unusual strong urges, talk to your healthcare provider.
- Decreased blood pressure (orthostatic hypotension). You may feel lightheaded or faint when
you rise too quickly from a sitting or lying position.
- Falls. ARISTADA INITIO and ARISTADA may make you sleepy or
dizzy when standing which may make you at risk for falls and related injuries.
- Low white blood cell count
- Seizures (convulsions)
- Problems controlling your body temperature. Avoid becoming too hot or dehydrated.
Do not exercise too much. In hot weather, stay inside in a cool place if possible. Stay out
of the sun. Do not wear too much clothing or heavy clothing. Drink plenty of water.
- Difficulty swallowing
The most common side effects of ARISTADA INITIO and
ARISTADA include restlessness or feeling like you need to move (akathisia). These are not all the
possible side effects of ARISTADA INITIO and ARISTADA. You should tell your
healthcare provider about any side-effects you have.
Do not drive, operate hazardous machinery, or do other dangerous activities until you know how
ARISTADA INITIO and ARISTADA affect you. ARISTADA
INITIO and ARISTADA may affect your judgment, thinking or motor skills.
Before receiving ARISTADA INITIO and ARISTADA tell your healthcare
provider about all of your medical conditions, including if you:
- have not taken Abilify®, Abilify Maintena®, or any aripiprazole product before
- have or had heart problems or a stroke
- have diabetes or high blood sugar or a family history of diabetes or high blood sugar. Your healthcare
provider should check your blood sugar before you receive ARISTADA INITIO
and/or ARISTADA and during your treatment with ARISTADA
- have or had low or high blood pressure
- have or had seizures (convulsions)
- have or had a low white blood cell count
- have problems that may affect you receiving an injection in your buttocks or your arm
- are pregnant or plan to become pregnant. It is not known if ARISTADA INITIO
and/or ARISTADA will harm your unborn baby. If you become pregnant while taking ARISTADA INITIO and/or ARISTADA, talk to your healthcare provider about
registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling 1-866-961-2388, or visit http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/
- are breastfeeding or plan to breastfeed. ARISTADA INITIO and/or ARISTADA
can pass into your breast milk. It is not known if it may harm your baby. Talk to your healthcare provider
about the best way to feed your baby if you receive ARISTADA INITIO and/or
ARISTADA.
Tell your healthcare provider about all the medicines you take, including
prescription and over-the-counter medicines, vitamins, and herbal supplements.
ARISTADA INITIO and ARISTADA and other medicines may affect each other causing
possible serious side effects. Do not start or stop any medicines after you receive ARISTADA INITIO and ARISTADA without talking to your healthcare provider first.
If you have any questions about your health or medicines, talk to your healthcare provider. You are
encouraged to report all side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
KELSEY: Sometimes when you have a lot of stress and chaotic things going on, you know, you just
need to take a break. And to me the beach is really calming and really relaxing, so I like to go down there. I
like to look at the beach and it’s like my serene—like my quiet place I guess you could say. You know, I like to
go and just think, like sit on the beach and, you know, think about life. And when I’m really stressed out, I
just take a little walk down to the beach. My mom is my rock, but, you know, some people might have friends and,
you know, coworkers or somebody else. You know, and I just think it’s important to have somebody on your side.
And, you know, having confidence in the person that is on your side and trusting them is obviously important. I
know that my mom will never ever stop fighting for me.
JULIAN: I like to play video games or write, watch Netflix, a lot of
stand-up comedy, stuff like that. Well, it’s important to have family around. Like my aunt, my
uncle, and my father, they’re really supportive of me. So, they’ve been there throughout the whole journey; so
them being there actually helps a lot. So, I’m grateful for that.